Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain
Abstract
For broad protection against infection by viruses such as influenza or HIV, vaccines should elicit antibodies that bind conserved viral epitopes, such as the receptor-binding site (RBS). RBS-directed antibodies have been described for both HIV and influenza virus, and the design of immunogens to elicit them is a goal of vaccine research in both fields. Residues in the RBS of influenza virus hemagglutinin (HA) determine a preference for the avian...
Paper Details
Title
Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain
Published Date
Dec 1, 2016
Journal
Volume
22
Issue
12
Pages
1465 - 1469
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